20α-Hydroxysteroid Dehydrogenase Activity in the Rabbit Ovary
نویسندگان
چکیده
منابع مشابه
Changes in Ovarian and Placental 20α-hydroxysteroid Dehydrogenase Activity during the Pregnancy in the Rat
The enzyme 20α-hydroxysteroid dehydrogenase (20α-HSD) catabolizes progesterone to 20α-dihydroprogesterone (20α-OHP), and is appeared in rat corpora luteal and placenta. A polled samples of 10-15 placental and ovarian tissues collected from each individual rat were subjected to measurement of 20α-HSD activity. A 20α-HSD activity in the cytosol fraction was based on the generation of NADPH. In th...
متن کاملThe transcription factor Ap-1 regulates monkey 20α-hydroxysteroid dehydrogenase promoter activity in CHO cells
BACKGROUND Monkey 20α-hydroxysteroid dehydrogenase (20α-HSD) is a catabolic enzyme responsible for converting progesterone into biologically inactive 20α-hydroxyprogesterone, thereby playing a key role in the estrous cycle or pregnancy and allowing ovulation and parturition to occur in most mammalian animals. Monkey 20α-HSD was highly abundant in ovarian and placental tissues during the pre-ovu...
متن کاملMolecular characterization of bovine placental and ovarian 20α-hydroxysteroid dehydrogenase
The enzyme 20α-hydroxysteroid dehydrogenase (20α-HSD) catalyzes the conversion of progesterone to its inactive form, 20α-hydroxyprogesterone. This enzyme plays a critical role in the regulation of luteal function in female mammals. In this study, we conducted the characterization and functional analyses of bovine 20α-HSD from placental and ovarian tissues. The nucleotide sequence of bovine 20α-...
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The type 2 isoform of human 17b-hydroxysteroid dehydrogenase (17bHSD2) efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. To obtain a better understanding of the regulation of local steroid biosynthesis and metabolism in human tissues, we have established a dual steroidogenic activity of the 17bHSD2 enzym...
متن کامل11Beta-hydroxysteroid dehydrogenase activity in spontaneously hypertensive and Dahl rats.
The role of the enzyme 11beta-hydroxysteroid dehydrogenase (11betaHSD) in hypertension remains unknown even if it appears that the inappropriately decreased 11betaHSD activity might be involved in a process that leads to high blood pressure. The possible changes of 11betaHSD were therefore investigated in rats with spontaneous or salt-induced hypertension. The adult male rats of the following g...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1972
ISSN: 0006-3363,1529-7268
DOI: 10.1093/biolreprod/6.1.78